IPOPT and Neural Dynamics Tips, Tricks and Diagnostics
نویسندگان
چکیده
We describe the process of fitting a phenomenological model for the spiking behavior of a zebra-fish neuron using the IPOPT routines described in Wächter and Biegler 2006. These routines provide a computationally efficient methods for estimating parameters in nonlinear differential equations. However, convergence to global solutions is not guaranteed and we describe a number of strategies that were necessary to obtain parameter estimates from these data. The intention of fitting these data was to improve on the phenomenological models used. The use of diagnostic techniques with IPOPT software is also described.
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